Overview of Picked Chemical Compounds and Intermediates

Overview of Picked Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity connected with bortezomib, a proteasome inhibitor Utilized in the treatment of various myeloma. Its synthesis or study is very important for guaranteeing the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound in the synthesis of imatinib, a drug that targets specific different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their analyze is vital for optimizing the output approach and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilized to deal with breast most cancers, and 3-dihydroisoindol-2-yl)piperidine-2 these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Utilized in the cure of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, that have several PMD applications, like antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which happen to be Employed in food, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication utilized to deal with kind 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).